The nucleolus is located approximately in the center of
            the nucleus.  It is a specialized region that plays an important role in protein
            synthesis.
Protein synthesis is the process of making a new
            protein.  Many organelles are involved in protein synthesis.  The process begins in the
            nucleolus, but also requires the ribosome, endoplasmic reticulum and golgi apparatus.
             You can also even say that the cytoplasm is required in addition to vessicles which
            transport the proteins during the process.
The main
            function of ribosomes is to make proteins.  Protein synthesis requires 3 types of RNA.
             It requires messenger RNA (mRNA), ribosomal RNA (rRNA) and transfer RNA (tRNA).  The
            job of the nucleolus is to make rRNA which helps in the production of ribosomes (which
            are needed to make proteins).
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