How did the German military and secret police attempt to discourage and defeat partisan and organized resistance in occupied Europe during World...

The Germans were pretty effective and methodical at
dealing with partisan and local resistance, though they never were able to completely
defeat it.  The most partisan activity took place in Yugoslavia, France and the Soviet
Union, where the Gestapo, the SS and the German Wehrmacht used trial and error combined
with brutality to attempt to deal with them.

Reprisals were
the most common method, where 50 civilians would be killed in the nearest village for
every German shot by the partisans.  This of course put a gigantic disincentive in place
and created some localized resistance to the partisans, or sometimes led to civilians
giving the Germans information about the resistance.  This was fairly rare,
however.

In Czechoslovakia, following the assassination of
SS Reichsprotektor Reinhard Heydrich in 1942, the nearby village of Lidice was razed,
the males in the town were executed, and the women and children deported to
concentration camps.  This was more extreme than most German reactions, but also seemed
to be more common on the Eastern Front, including in the Soviet
Union.

The Germans were also very effective at gathering
intelligence, in part because their police organizations and SS had absolute authority
over local populations and could use any method of intelligence gathering or torture
that they wished to.